Autor: |
Pinaki Misra, Ravindra Kodali, Saketh Chemuru, Karunakar Kar, Ronald Wetzel |
Jazyk: |
angličtina |
Rok vydání: |
2016 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/ncomms12419 |
Popis: |
The elucidation of amyloid nucleation mechanisms remains challenging as early oligomeric intermediates are transient and difficult to distinguish. Here the authors use Aβ- polyglutamine hybrid peptides designed to slow and limit amyloid maturation to provide insights into the structures of Aβ self-assembly intermediates. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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