Autor: |
Jan Franko, Viet H. Le, May C. Tee, Mayin Lin, Jessica Sedinkin, Shankar Raman, Daniela Frankova |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Cancer Treatment and Research Communications, Vol 29, Iss , Pp 100475- (2021) |
Druh dokumentu: |
article |
ISSN: |
2468-2942 |
DOI: |
10.1016/j.ctarc.2021.100475 |
Popis: |
Background: Signet ring cell carcinoma (SRCC) is a distinct malignancy occurring across the tubular gastrointestinal tract (tGIT). We comprehensively examined the outcomes of patients diagnosed with SRCC across tGIT. Methods: SRCC and not-otherwise-specified adenocarcinoma (NOS) patients reported to the National Cancer Database from 2004 to 2015 were included. Baseline characteristics, outcomes and site-specific adjusted hazard ratios (aHR) derived from Cox models of SRCC patients were compared to those of NOS patients. Overall survival (OS) was primary endpoint. Results: A total of 41,686 SRCC (4.6%) and 871,373 NOS patients (95.4%) were included. SRCC patients were younger (63.1 ± 14.7 vs. 67.0 ± 13.4 y, p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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