Measurement of troponin in cardiomyopathies
Autor: | Andrew Connelly, Iain N. Findlay, Caroline J. Coats |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: | |
Zdroj: | Cardiogenetics, Vol 6, Iss 1 (2016) |
Druh dokumentu: | article |
ISSN: | 2035-8253 2035-8148 |
DOI: | 10.4081/cardiogenetics.2016.6306 |
Popis: | Troponins are thin myofilament proteins that regulate the contraction of cardiac and skeletal muscle. The cardio-specific troponin I (TnI) and T (TnT) proteins are sensitive and specific biomarkers of myocardial injury which over the past twenty years have revolutionised the diagnosis and management of myocardial infarction. With the advent of high sensitivity assays the role for cardiac troponins is possibly expanding. Elevated levels are associated with adverse cardiovascular events and mortality in heart failure and the general population. Studies in cardiomyopathies are generally small with |
Databáze: | Directory of Open Access Journals |
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