Measurement of troponin in cardiomyopathies

Autor: Andrew Connelly, Iain N. Findlay, Caroline J. Coats
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Cardiogenetics, Vol 6, Iss 1 (2016)
Druh dokumentu: article
ISSN: 2035-8253
2035-8148
DOI: 10.4081/cardiogenetics.2016.6306
Popis: Troponins are thin myofilament proteins that regulate the contraction of cardiac and skeletal muscle. The cardio-specific troponin I (TnI) and T (TnT) proteins are sensitive and specific biomarkers of myocardial injury which over the past twenty years have revolutionised the diagnosis and management of myocardial infarction. With the advent of high sensitivity assays the role for cardiac troponins is possibly expanding. Elevated levels are associated with adverse cardiovascular events and mortality in heart failure and the general population. Studies in cardiomyopathies are generally small with
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