Autor: |
Yue Zhao, Meng-Fei Zhao, Shan Jiang, Jing Wu, Jia Liu, Xian-Wen Yuan, Di Shen, Jing-Zi Zhang, Nan Zhou, Jian He, Lei Fang, Xi-Tai Sun, Bin Xue, Chao-Jun Li |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-020-14450-6 |
Popis: |
Extracellular vesicles (EVs) containing miRNAs or proteins can coordinate metabolic responses between tissues. Here the authors demonstrate that during lipid overload, the liver secretes miRNA-containing EVs through a Ggpps-Rab27 dependent mechanism, which controls adipose tissue lipid storage capacity. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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