Autor: |
Julien Pierrard, Sofie Heylen, Ad Vandermeulen, Geneviève Van Ooteghem |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Technical Innovations & Patient Support in Radiation Oncology, Vol 32, Iss , Pp 100277- (2024) |
Druh dokumentu: |
article |
ISSN: |
2405-6324 |
DOI: |
10.1016/j.tipsro.2024.100277 |
Popis: |
Introduction: Intra- and inter-fraction rectum motion is important for pelvic radiotherapy (RT). This study assesses how RT session duration, the presence or the absence of an intra-rectal tumour, and the distance from the anorectal junction (ARJd) impact rectal motion. Materials and methods: Analyses used cone-beam computed tomographies (CBCTs) from RT patients treated for rectal and prostate cancer. Three structures were evaluated: (1) the entire rectum in patients without a rectal tumour (RectumProstate); (2) the non-invaded portion (RectumRectum) and (3) the tumour-invaded portion (RectumTumour) in rectal cancer patients.Intrafraction motion was assessed using the Hausdorff distance 95% and the Mean distance-to-agreement between structures delineated on the first CBCT and the 2 subsequent CBCTs within a same RT session. Interfraction motion was quantified by comparing structures delineated on the planning-CT and the first CBCT of each session.Linear mixed model evaluated rectum motion in relation to time, tumour presence, and ARJd, respectively. Results: We included 10 patients with and 10 without rectal cancer, collecting 385 CBCTs. A significant correlation (p RectumRectum and RectumTumour, p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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