17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line

Autor: Margarida Castro-Caldas, Carlos B. Duarte, Arsélio P. Carvalho, M. Celeste Lopes
Jazyk: angličtina
Rok vydání: 2001
Předmět:
Zdroj: Mediators of Inflammation, Vol 10, Iss 5, Pp 245-251 (2001)
Druh dokumentu: article
ISSN: 0962-9351
1466-1861
DOI: 10.1080/09629350120093713
Popis: Aims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory actions of the steroid hormones, the purpose of this study was to investigate the effects of the female sex steroid hormone, 17β-estradiol (E2β), on the synthesis and secretion of ANXA1 in the human CCRF-CEM acute lymphoblastic leukemia cell line.
Databáze: Directory of Open Access Journals