17β-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line
Autor: | Margarida Castro-Caldas, Carlos B. Duarte, Arsélio P. Carvalho, M. Celeste Lopes |
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Jazyk: | angličtina |
Rok vydání: | 2001 |
Předmět: | |
Zdroj: | Mediators of Inflammation, Vol 10, Iss 5, Pp 245-251 (2001) |
Druh dokumentu: | article |
ISSN: | 0962-9351 1466-1861 |
DOI: | 10.1080/09629350120093713 |
Popis: | Aims: Annexin I (ANXA1), a 37 kDa member of the annexin family of Ca2+-binding and phospholipidbinding proteins, is particularly abundant in various populations of peripheral blood leukocytes. Since this protein modulates the anti-inflammatory actions of the steroid hormones, the purpose of this study was to investigate the effects of the female sex steroid hormone, 17β-estradiol (E2β), on the synthesis and secretion of ANXA1 in the human CCRF-CEM acute lymphoblastic leukemia cell line. |
Databáze: | Directory of Open Access Journals |
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