Autor: |
Didier Villemin, Florian Faucher, Nathalie Bar, Zahira Kibou, Noureddine Choukchou-Braham |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
|
Zdroj: |
Chemistry Proceedings, Vol 8, Iss 1, p 74 (2021) |
Druh dokumentu: |
article |
ISSN: |
2673-4583 |
DOI: |
10.3390/ecsoc-25-11676 |
Popis: |
Ricinine is an alkaloid of Ricinus communis that displays numerous biological properties. Ricinine (4-methoxy-1-methyl-2-oxo-dihydropyridine-3-carbonitrile)) and new N-analogues of Ricinine were obtained by the reaction of ethyl α-ethoxyethylidenecyanoacetate with various amines. Earlier, ethyl α-ethoxyethylidenecyanoacetate was easily prepared from ethyl cyanoacetate. Biologically, amines such as tryptamine and histamine were used in order to introduce a second pharmacophore on the target molecule. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|