Blue-grey hyperpigmentation in acne after vandetanib therapy and doxycycline use: A case report
Autor: | Jonah W Perlmutter, Rachel C Cogan, Marni C Wiseman |
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Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: | |
Zdroj: | SAGE Open Medical Case Reports, Vol 10 (2022) |
Druh dokumentu: | article |
ISSN: | 2050-313X 2050313X |
DOI: | 10.1177/2050313X221086316 |
Popis: | Vandetanib is an oral tyrosine kinase inhibitor with cutaneous adverse effects that include the development of acne. We present a patient who underwent vandetanib therapy for stage IV medullary thyroid cancer in conjunction with the use of doxycycline for acne that developed. After vandetanib use, blue-grey pigmentation developed in the acne on his face, chest, back, and arms, which darkened after the use of doxycycline. We review the literature to report that this blue-grey hyperpigmentation was likely vandetanib-induced but may have been the result of both drugs being used in combination. |
Databáze: | Directory of Open Access Journals |
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