Mitochondrial DNA Copy Number in Peripheral Blood Is Reduced in Type 2 Diabetes Patients with Polyneuropathy and Associated with a
Autor: | Andrea, Latini, Paola, Borgiani, Giada, De Benedittis, Cinzia, D'Amato, Carla, Greco, Davide, Lauro, Giuseppe, Novelli, Vincenza, Spallone, Cinzia, Ciccacci |
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Rok vydání: | 2020 |
Předmět: | |
Zdroj: | DNA and cell biology. 39(8) |
ISSN: | 1557-7430 |
Popis: | Our aim was to evaluate in a cohort of 125 Italian patients with type 2 diabetes (T2D), who underwent neurological evaluation, the possible differences in the number of mitochondrial DNA copies (mtDNA) comparing positive and negative patients for cardiovascular autonomic neuropathy (CAN) or diabetic peripheral neuropathy (DPN) and comparing them with healthy controls. We also investigated a possible correlation of the number of mtDNA copies with the polymorphism rs3746444 of the |
Databáze: | OpenAIRE |
Externí odkaz: |
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