In situ synthesis of peptide microarrays using ink-jet microdispensing

Autor: Bogdan V, Antohe, Patrick W, Cooley
Rok vydání: 2007
Předmět:
Zdroj: Methods in molecular biology (Clifton, N.J.). 381
ISSN: 1064-3745
Popis: The study of protein-protein and protein-DNA interactions is critical to understand biological processes. This article presents the methodology to create peptide microarrays in situ for the high-throughput screening of complex biomolecules. The in situ ink-jet peptide synthesis results in a conservation of costly reagent and amino acids, whereas providing a means to produce denser peptide arrays. A smaller amount of test sample is required to observe interaction when using these high-density peptide arrays.
Databáze: OpenAIRE