Effect of prostaglandin E1 on bile flow in the rat
Autor: | C F, Nassar, M, Massad, Z, Habbal |
---|---|
Rok vydání: | 1984 |
Předmět: | |
Zdroj: | Digestion. 29(4) |
ISSN: | 0012-2823 |
Popis: | The effect of intravenous administration of prostaglandin E1 on bile flow in the rat was investigated. PGE1 infused at concentrations of 4.5, 7.5 and 15 micrograms/kg body weight/min caused an initial increase in bile acid-independent bile flow rate which peaked within 30 min and was followed by a significant decrease (p less than 0.01) below the control value. However, PGE1 administered intravenously at an infusion rate of 15 micrograms X kg-1 X min-1 showed a significant decrease (p less than 0.01) in bile acid-dependent bile flow rate. |
Databáze: | OpenAIRE |
Externí odkaz: |