Effect of prostaglandin E1 on bile flow in the rat

Autor: C F, Nassar, M, Massad, Z, Habbal
Rok vydání: 1984
Předmět:
Zdroj: Digestion. 29(4)
ISSN: 0012-2823
Popis: The effect of intravenous administration of prostaglandin E1 on bile flow in the rat was investigated. PGE1 infused at concentrations of 4.5, 7.5 and 15 micrograms/kg body weight/min caused an initial increase in bile acid-independent bile flow rate which peaked within 30 min and was followed by a significant decrease (p less than 0.01) below the control value. However, PGE1 administered intravenously at an infusion rate of 15 micrograms X kg-1 X min-1 showed a significant decrease (p less than 0.01) in bile acid-dependent bile flow rate.
Databáze: OpenAIRE