[AMP deaminase activity in hyperoxia and the effect of AMP on animal sensitivity to oxygen under pressure]

Autor: I A, Goroshinskaia, Z G, Bronovitskaia
Rok vydání: 1991
Předmět:
Zdroj: Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. 77(2)
ISSN: 0015-329X
Popis: Under the effects of 0.7 MPa of oxygen leading to a convulsive state, AMP-deaminase activity increased significantly in the rat brain mitochondrial fraction with only a tendency to increase in cytoplasmic fraction. Stimulated effects of the enzyme allosteric activator ATP is more obvious in intact animals than in hyperoxic ones. Pretreatment with AMP before hyperoxygenation exerts a protective effect preventing the alteration of monoamine oxydase catalytic properties, stabilizing membrane structure and improving the general state of the animals.
Databáze: OpenAIRE