| Autor: |
L B, Popova, Iu V, Panchin |
| Rok vydání: |
1998 |
| Předmět: |
|
| Zdroj: |
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. 48(2) |
| ISSN: |
0044-4677 |
| Popis: |
FITC-labelled alpha-bungarotoxin (alpha BT[FITC]) was used to identify acetylcholine (ACh)-sensitive neurons in the central nervous system of pteropod mollusc Clione limacina. Two small symmetrical neurons were stained with alpha BT[FITC] on the dorsal surface of the cerebral ganglia. The staining was highly specific as it was completely blocked by preincubation in alpha-bungarotoxin [alpha BT] at very low concentration (10(-9) M). Nicotinic agonists and antagonists efficiently prevented alpha BT[FITC] staining while muscarinic agonists and antagonists had no effect. These findings confirm the suggestion that alpha BT[FITC] binds to nicotinic ACh receptors. The possible role is discussed of alpha BT[FITC]-stained cells in the complex of hunting behavior of Clione. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
