Autor: |
R J, Vavrek, L, Gera, J M, Stewart |
Rok vydání: |
1992 |
Předmět: |
|
Zdroj: |
Agents and actions. Supplements. 38 |
ISSN: |
0379-0363 |
Popis: |
More than 200 new analogs of bradykinin have been synthesized and assayed. Analogs containing a D-aliphatic amino acid residue at position 7 and an L-aliphatic residue at position 8 are very potent antagonists of BK action on classical systems. Thus the "conventional wisdom" that a D-aromatic amino acid residue is required at sequence position 7 of BK antagonists must be modified. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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