Wegener's granulomatosis and alpha1-antitrypsin-deficiency emphysema: proteinase-related diseases

Autor:	V T, Barnett, M, Sekosan, A, Khurshid
Rok vydání:	1999
Předmět:	Adult Pulmonary Emphysema alpha 1-Antitrypsin alpha 1-Antitrypsin Deficiency Granulomatosis with Polyangiitis Humans Female Lung Alleles
Zdroj:	Chest. 116(1)
ISSN:	0012-3692
Popis:	Wegener's granulomatosis (WG) and alpha1-antitrypsin (alpha1-AT)-deficiency emphysema are both uncommon disorders. A relationship may exist between these diseases involving the proteinase and antiproteinase balance in the lung. A case is presented of WG and alpha1-AT-deficiency emphysema occurring in the same patient. Previous studies concerning the correlation between abnormal alpha1-AT alleles and WG are discussed. Potential mechanisms for the relationship and recommendations for screening are given.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::3d74695173fd7c171c3df3cc477e3ae4 https://pubmed.ncbi.nlm.nih.gov/10424537 Zobrazit plný text záznamu