Autor: |
Mehmet, Kanbay, Yalcin, Solak, Baris, Afsar, Ionut, Nistor, Gamze, Aslan, Ozlem Hilal, Çağlayan, Asli, Aykanat, Mihaela-Dora, Donciu, Miguel A, Lanaspa, Ahsan A, Ejaz, Richard J, Johnson, Adrian, Covic |
Rok vydání: |
2016 |
Předmět: |
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Zdroj: |
Angiology. 68(2) |
ISSN: |
1940-1574 |
Popis: |
Contrast-induced acute kidney injury (CI-AKI) is a common cause of hospital-acquired acute kidney injury (AKI). We evaluated the evidence that uric acid (UA) plays a pathogenic role in CI-AKI. Ten studies were eligible for inclusion for meta-analysis. Hyperuricemia predicted risk for cases with AKI in prospective cohort studies. Higher levels of serum UA (SUA), as defined by the authors, were associated with a 2-fold increased risk to develop AKI (pooled odds ratio 2.03; 95% confidence interval [CI] 1.48-2.78). Significant heterogeneity was found in cohort studies ( P = .001, I |
Databáze: |
OpenAIRE |
Externí odkaz: |
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