Association between the MB system and asthma in the Japanese
| Autor: | Akemi Wakisaka, Toyoko Kano, Kaname Togashi, Junko Moriuchi, Yuko Nakai, Yoshinori Wagatsuma, Yukio Sakiyama, Hiromi Tsuneta, Miki Aizawa, Shuzo Matsumoto |
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| Rok vydání: | 1982 |
| Předmět: |
Genes
MHC Class II Immunology Locus (genetics) Human leukocyte antigen Immunoglobulin E Radioallergosorbent Test Japan Antigen HLA Antigens HLA-B Antigens medicine Humans Immunology and Allergy Asthma biology medicine.diagnostic_test business.industry Radioallergosorbent test Histocompatibility Antigens Class II HLA-DR Antigens General Medicine medicine.disease respiratory tract diseases Relative risk biology.protein business |
| Zdroj: | Human Immunology. 4:265-270 |
| ISSN: | 0198-8859 |
| DOI: | 10.1016/0198-8859(82)90042-8 |
| Popis: | Twenty-three unrelated Japanese patients with asthma who showed a high total serum IgE level, a strong skin test response to Dermatophagoides farinae, and a high score on a radioallergosorbent test (RAST) using Dermatophagoides farinae were typed for HLA-A locus, -B locus, and -D region antigens. No significant difference in the frequencies of HLA-A, -B, and -DR antigens were observed between the asthma patients and the healthy controls. A significant difference in the frequency of MB3', however, was found between the asthma patients and the healthy controls (corrected p = 0.04, relative risk = 18.5). |
| Databáze: | OpenAIRE |
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