| Autor: |
Avnioğlu, Seda, Güngör, Meltem, Kurutaş, Ergül, Öztürk, Ünal, Demirhan, İlter, Bakariş, Sevgi, Velioğlu, Halil Aziz, Çankaya, Şeyda, Yuluğ, Burak |
| Přispěvatelé: |
ALKÜ, Fakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Revista Romana de Medicina de Laborator. 30:9-18 |
| ISSN: |
2284-5623 |
| DOI: |
10.2478/rrlm-2021-0036 |
| Popis: |
Objectives: Resveratrol (RSV) is a natural polyphenolic compound showing significant antioxidant effects. In this study, we aimed to investigate the effects of resveratrol on the sphingosine-1-phosphate (S1P) and oxidative stress biomarkers in hearth ischemia-reperfusion (I/R). Materials and Methods: The biochemical and histopathological effects of RSV on cardiac ischemia-reperfusion injury were investigated through ELISA- and light microscope. Results: We observed statistically significant differences between the treatment group and the control group in terms of malondialdehyde (MDA) level, catalase (CAT) and superoxide dismutase (SOD) activities (p Conclusion: Resveratrol may play an important role in cardiac I/R injury through its anti-inflammatory and antioxidant effects which were biochemically and histopathologically confirmed in the present study. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
