The effect of lactoferrin in aging: role and potential
Autor: | Chang-Jing Wu, Xiaomeng Liu, Weifeng Peng, Jin Li, Bing Li, Henan Liu, Bo Zhang, Fuli Zhang, Kuntong Han, Fan Shuhua, Xudong Liu, Yidan zheng |
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Rok vydání: | 2022 |
Předmět: |
Senescence
Aging medicine.medical_specialty media_common.quotation_subject Anti-Inflammatory Agents Psychological intervention Disease Protective Agents Bioinformatics Models Biological Mice Human health Diabetes mellitus medicine Animals Humans media_common biology business.industry Lactoferrin Public health Longevity General Medicine medicine.disease biology.protein business Food Science |
Zdroj: | Food & Function. 13:501-513 |
ISSN: | 2042-650X 2042-6496 |
DOI: | 10.1039/d1fo02750f |
Popis: | Aging is frequently accompanied by various types of physiological deterioration, which increases the risk of human pathologies. Global public health efforts to increase human lifespan has been increasingly focusing on lowering the risk of incidences of aging-related disease, such as diabetes, neurodegenerative diseases, cardiovascular disease and cancers. Dietary interventions is a promising approach to maintain human health during aging. Lactoferrin (LF) is known for its physiologically pleiotropic properties. Anti-aging interventions of LF have proven to be safe and effective for various pharmacological activities such as antioxidants, anti-cellular senescence, anti-inflammation, and anti-carcinogenic. As well as the pivotal role of LF on the modulating of major signaling pathways that influence longevity of organisms. Thus, LF is expected to be able to attenuate the process of aging and greatly ameliorate its effects. |
Databáze: | OpenAIRE |
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