The effect of lactoferrin in aging: role and potential

Autor: Chang-Jing Wu, Xiaomeng Liu, Weifeng Peng, Jin Li, Bing Li, Henan Liu, Bo Zhang, Fuli Zhang, Kuntong Han, Fan Shuhua, Xudong Liu, Yidan zheng
Rok vydání: 2022
Předmět:
Zdroj: Food & Function. 13:501-513
ISSN: 2042-650X
2042-6496
DOI: 10.1039/d1fo02750f
Popis: Aging is frequently accompanied by various types of physiological deterioration, which increases the risk of human pathologies. Global public health efforts to increase human lifespan has been increasingly focusing on lowering the risk of incidences of aging-related disease, such as diabetes, neurodegenerative diseases, cardiovascular disease and cancers. Dietary interventions is a promising approach to maintain human health during aging. Lactoferrin (LF) is known for its physiologically pleiotropic properties. Anti-aging interventions of LF have proven to be safe and effective for various pharmacological activities such as antioxidants, anti-cellular senescence, anti-inflammation, and anti-carcinogenic. As well as the pivotal role of LF on the modulating of major signaling pathways that influence longevity of organisms. Thus, LF is expected to be able to attenuate the process of aging and greatly ameliorate its effects.
Databáze: OpenAIRE