Risk assessment for hospital admission in patients with COPD; a multi-centre UK prospective observational study

Autor: Marie Fisk, John R. Cockcroft, Divya Mohan, Jilles M Fermont, Angela M. Wood, Charlotte E. Bolton, Michael I. Polkey, Ian B. Wilkinson, Jonathan Fuld, Hana Müllerová, William MacNee, Joseph Cheriyan, Carmel M. McEniery, Ruth Tal-Singer
Přispěvatelé: Fermont, Jilles M [0000-0001-5042-5785], Bolton, Charlotte E [0000-0002-9578-2249], Fisk, Marie [0000-0002-1292-7642], Cheriyan, Joseph [0000-0001-6921-1592], Tal-Singer, Ruth [0000-0002-5275-8062], Polkey, Michael I [0000-0003-1243-8571], Müllerova, Hana [0000-0002-0949-0101], Apollo - University of Cambridge Repository, Fermont, Jilles M. [0000-0001-5042-5785], Bolton, Charlotte E. [0000-0002-9578-2249], Polkey, Michael I. [0000-0003-1243-8571]
Rok vydání: 2020
Předmět:
Male
Longitudinal study
Pulmonology
Exacerbation
Physiology
Walking
Pathology and Laboratory Medicine
Biochemistry
Body Mass Index
Pulmonary Disease
Chronic Obstructive

0302 clinical medicine
Patient Admission
Heart Rate
Health care
Outcome Assessment
Health Care

Medicine and Health Sciences
Coughing
030212 general & internal medicine
Longitudinal Studies
Prospective Studies
Prospective cohort study
COPD
Multidisciplinary
Middle Aged
Physical Functional Performance
Hospitals
3. Good health
Hospitalization
Physiological Parameters
Medicine
Female
Risk assessment
Research Article
Glomerular Filtration Rate
medicine.medical_specialty
Science
Chronic Obstructive Pulmonary Disease
Cardiology
Risk Assessment
03 medical and health sciences
Signs and Symptoms
Diagnostic Medicine
medicine
Humans
Aged
Renal Physiology
Biological Locomotion
business.industry
Body Weight
Biology and Life Sciences
Length of Stay
medicine.disease
United Kingdom
Health Care
030228 respiratory system
Health Care Facilities
Emergency medicine
Observational study
Physiological Processes
business
Body mass index
Biomarkers
Zdroj: PLoS ONE
PLoS ONE, Vol 15, Iss 2, p e0228940 (2020)
Popis: In chronic obstructive pulmonary disease (COPD), acute exacerbation of COPD requiring hospital admission is associated with mortality and healthcare costs. The ERICA study assessed multiple clinical measures in people with COPD, including the short physical performance battery (SPPB), a simple test of physical function with 3 components (gait speed, balance and sit-to-stand). We tested the hypothesis that SPPB score would relate to risk of hospital admissions and length of hospital stay. Data were analysed from 714 of the total 729 participants (434 men and 280 women) with COPD. Data from this prospective observational longitudinal study were obtained from 4 secondary and 1 tertiary centres from England, Scotland, and Wales. The main outcome measures were to estimate the risk of hospitalisation with acute exacerbation of COPD (AECOPD and length of hospital stay derived from hospital episode statistics (HES). In total, 291 of 714 individuals experienced 762 hospitalised AECOPD during five-year follow up. Poorer performance of SPPB was associated with both higher rate (IRR 1.08 per 1 point decrease, 95% CI 1.01 to 1.14) and increased length of stay (IRR 1.18 per 1 point decrease, 95% CI 1.10 to 1.27) for hospitalised AECOPD. For the individual sit-to-stand component of the SPPB, the association was even stronger (IRR 1.14, 95% CI 1.02 to 1.26 for rate and IRR 1.32, 95% CI 1.16 to 1.49 for length of stay for hospitalised AECOPD). The SPPB, and in particular the sit-to-stand component can both evaluate the risk of H-AECOPD and length of hospital stay in COPD. The SPPB can aid in clinical decision making and when prioritising healthcare resources.
Databáze: OpenAIRE
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