Risk assessment for hospital admission in patients with COPD; a multi-centre UK prospective observational study
| Autor: | Marie Fisk, John R. Cockcroft, Divya Mohan, Jilles M Fermont, Angela M. Wood, Charlotte E. Bolton, Michael I. Polkey, Ian B. Wilkinson, Jonathan Fuld, Hana Müllerová, William MacNee, Joseph Cheriyan, Carmel M. McEniery, Ruth Tal-Singer |
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| Přispěvatelé: | Fermont, Jilles M [0000-0001-5042-5785], Bolton, Charlotte E [0000-0002-9578-2249], Fisk, Marie [0000-0002-1292-7642], Cheriyan, Joseph [0000-0001-6921-1592], Tal-Singer, Ruth [0000-0002-5275-8062], Polkey, Michael I [0000-0003-1243-8571], Müllerova, Hana [0000-0002-0949-0101], Apollo - University of Cambridge Repository, Fermont, Jilles M. [0000-0001-5042-5785], Bolton, Charlotte E. [0000-0002-9578-2249], Polkey, Michael I. [0000-0003-1243-8571] |
| Rok vydání: | 2020 |
| Předmět: |
Male
Longitudinal study Pulmonology Exacerbation Physiology Walking Pathology and Laboratory Medicine Biochemistry Body Mass Index Pulmonary Disease Chronic Obstructive 0302 clinical medicine Patient Admission Heart Rate Health care Outcome Assessment Health Care Medicine and Health Sciences Coughing 030212 general & internal medicine Longitudinal Studies Prospective Studies Prospective cohort study COPD Multidisciplinary Middle Aged Physical Functional Performance Hospitals 3. Good health Hospitalization Physiological Parameters Medicine Female Risk assessment Research Article Glomerular Filtration Rate medicine.medical_specialty Science Chronic Obstructive Pulmonary Disease Cardiology Risk Assessment 03 medical and health sciences Signs and Symptoms Diagnostic Medicine medicine Humans Aged Renal Physiology Biological Locomotion business.industry Body Weight Biology and Life Sciences Length of Stay medicine.disease United Kingdom Health Care 030228 respiratory system Health Care Facilities Emergency medicine Observational study Physiological Processes business Body mass index Biomarkers |
| Zdroj: | PLoS ONE PLoS ONE, Vol 15, Iss 2, p e0228940 (2020) |
| Popis: | In chronic obstructive pulmonary disease (COPD), acute exacerbation of COPD requiring hospital admission is associated with mortality and healthcare costs. The ERICA study assessed multiple clinical measures in people with COPD, including the short physical performance battery (SPPB), a simple test of physical function with 3 components (gait speed, balance and sit-to-stand). We tested the hypothesis that SPPB score would relate to risk of hospital admissions and length of hospital stay. Data were analysed from 714 of the total 729 participants (434 men and 280 women) with COPD. Data from this prospective observational longitudinal study were obtained from 4 secondary and 1 tertiary centres from England, Scotland, and Wales. The main outcome measures were to estimate the risk of hospitalisation with acute exacerbation of COPD (AECOPD and length of hospital stay derived from hospital episode statistics (HES). In total, 291 of 714 individuals experienced 762 hospitalised AECOPD during five-year follow up. Poorer performance of SPPB was associated with both higher rate (IRR 1.08 per 1 point decrease, 95% CI 1.01 to 1.14) and increased length of stay (IRR 1.18 per 1 point decrease, 95% CI 1.10 to 1.27) for hospitalised AECOPD. For the individual sit-to-stand component of the SPPB, the association was even stronger (IRR 1.14, 95% CI 1.02 to 1.26 for rate and IRR 1.32, 95% CI 1.16 to 1.49 for length of stay for hospitalised AECOPD). The SPPB, and in particular the sit-to-stand component can both evaluate the risk of H-AECOPD and length of hospital stay in COPD. The SPPB can aid in clinical decision making and when prioritising healthcare resources. |
| Databáze: | OpenAIRE |
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