Tumor Detection and Localization with99mTc-Tetracycline

Autor:	Mrinal K. Dewanjee, Michael Davis, Arthur T. Skarin, William D. Kaplan, Christian P. Fliegel, John T. Chaffey, David S. Rosenthal, B. Leonard Holman
Rok vydání:	1974
Předmět:	Pathology medicine.medical_specialty Carcinoma Hepatocellular Lung Neoplasms Tetracycline medicine.medical_treatment Urinary system Gallium Adenocarcinoma Mediastinal Neoplasms Nitrosourea Compounds Mice Muscular Diseases medicine Animals Humans Transplantation Homologous Radiology Nuclear Medicine and imaging Neoplasm Metastasis Radionuclide Imaging Radioisotopes Osteosarcoma Chemotherapy L-Lactate Dehydrogenase business.industry Liver Neoplasms Technetium Sarcoma Neoplasms Experimental Hodgkin Disease Rats Radiation therapy Tumor detection Carcinoma Bronchogenic medicine.anatomical_structure Abdomen Rabbits Sarcoma Experimental Glioblastoma business Methane Neoplasm Transplantation medicine.drug
Zdroj:	Radiology. 112:147-154
ISSN:	1527-1315 0033-8419
DOI:	10.1148/112.1.147
Popis:	The use of 99mTc-tetracycline as a tumor-localizing agent for external scanning was assessed in rats, mice, rabbits and man. Tumors were successfully delineated in 14 of 18 patients studied. Chemotherapy and radiotherapy appeared to inhibit tumor uptake of 99mTc-tetracycline; background activity due to uptake by the gastrointestinal and urinary tracts diminished detection of tumors within the abdomen. Outside of the abdomen, patient scintiscans accurately demonstrated the number and extent of the lesions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b81d5480d96bd3de58fe5a817b3c0b https://doi.org/10.1148/112.1.147 Zobrazit plný text záznamu