Cell signaling and regulation of CFTR expression in cystic fibrosis cells in the era of high efficiency modulator therapy

Autor:	Alessandra Ghigo, Chiara De Santi, Merrill Hart, Nilay Mitash, Agnieszka Swiatecka-Urban
Rok vydání:	2023
Předmět:	Pulmonary and Respiratory Medicine Pediatrics Perinatology and Child Health
Zdroj:	Journal of Cystic Fibrosis. 22:S12-S16
ISSN:	1569-1993
DOI:	10.1016/j.jcf.2022.12.015
Popis:	Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP- and protein kinase A (PKA)-regulated channel, expressed on the luminal surface of secretory and absorptive epithelial cells. CFTR has a complex, cell-specific regulatory network playing a major role in cAMP- and Ca
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb8203ae946c3f00397d3844e21daba https://doi.org/10.1016/j.jcf.2022.12.015 Zobrazit plný text záznamu Full Text from ScienceDirect