Cell signaling and regulation of CFTR expression in cystic fibrosis cells in the era of high efficiency modulator therapy
| Autor: | Alessandra Ghigo, Chiara De Santi, Merrill Hart, Nilay Mitash, Agnieszka Swiatecka-Urban |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Journal of Cystic Fibrosis. 22:S12-S16 |
| ISSN: | 1569-1993 |
| DOI: | 10.1016/j.jcf.2022.12.015 |
| Popis: | Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP- and protein kinase A (PKA)-regulated channel, expressed on the luminal surface of secretory and absorptive epithelial cells. CFTR has a complex, cell-specific regulatory network playing a major role in cAMP- and Ca |
| Databáze: | OpenAIRE |
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