Physical Exercise and Liver Autophagy: Potential Roles of IL-6 and Irisin
Autor: | Ana P, Pinto, Eduardo R, Ropelle, Joe, Quadrilatero, Adelino S R, da Silva |
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Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Exercise and Sport Sciences Reviews. 50:89-96 |
ISSN: | 1538-3008 0091-6331 |
DOI: | 10.1249/jes.0000000000000278 |
Popis: | Autophagic dysregulation contributes to liver diseases. Although some investigations have examined the effects of endurance and resistance exercise on autophagy activation, potential myokines responsible for skeletal muscle-liver crosstalk are still unknown. Based on experimental studies and bioinformatics, we hypothesized that interleukin 6 (IL-6) and irisin might be key players in the contraction-induced release of molecules that regulate liver autophagic responses. |
Databáze: | OpenAIRE |
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