Complexes of Glucarolactones with Water-Soluble Copolymers of N-Vinylpyrrolidone with N-Vinylamine as Inhibitors of β-Glucuronidase Efficacy

Autor: Valerii D. Krasikov, Yulia G. Santuryan, Irina I. Malahova, Alexey G. Ivanov, Nikolay I. Gorshkov, Evgenii F. Panarin
Rok vydání: 2021
Předmět:
Zdroj: Polymers
Polymers; Volume 14; Issue 1; Pages: 105
Polymers, Vol 14, Iss 105, p 105 (2022)
ISSN: 2073-4360
Popis: Water-soluble complexes of N-vinylpyrrolidone/N-vinylamine copolymers with lactones of D-glucuronic acid were obtained and characterized by chromatographic, spectral, and hydrodynamic methods. The complexes efficiently inhibited the enzyme β-glucuronidase that causes the appearance of bladder tumors. The products demonstrated prolonged action and were stable during storage.
Databáze: OpenAIRE