Complexes of Glucarolactones with Water-Soluble Copolymers of N-Vinylpyrrolidone with N-Vinylamine as Inhibitors of β-Glucuronidase Efficacy
Autor: | Valerii D. Krasikov, Yulia G. Santuryan, Irina I. Malahova, Alexey G. Ivanov, Nikolay I. Gorshkov, Evgenii F. Panarin |
---|---|
Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Polymers Polymers; Volume 14; Issue 1; Pages: 105 Polymers, Vol 14, Iss 105, p 105 (2022) |
ISSN: | 2073-4360 |
Popis: | Water-soluble complexes of N-vinylpyrrolidone/N-vinylamine copolymers with lactones of D-glucuronic acid were obtained and characterized by chromatographic, spectral, and hydrodynamic methods. The complexes efficiently inhibited the enzyme β-glucuronidase that causes the appearance of bladder tumors. The products demonstrated prolonged action and were stable during storage. |
Databáze: | OpenAIRE |
Externí odkaz: |