Surprising lack of association of prior alcohol consumption on hepatitis C infection and hepatic histology

Autor: Manjushree Gautam, Brenda Horwitz, Swati Patel, Martin Black, Alan W Chang, Frank K. Friedenberg
Rok vydání: 2003
Předmět:
Zdroj: The American Journal of Gastroenterology. 98:S84
ISSN: 0002-9270
DOI: 10.1016/s0002-9270(03)01014-1
Popis: Background: Chronic alcoholism is common in patients with chronic hepatitis C (CHC) infection. Alcohol can exacerbate liver damage in hepatitis C infection by causing oxidative stress. Heavy alcohol consumption has been associated with higher levels of viremia and more advanced fibrosis. Studies have also suggested that chronic alcoholism causes more rapid progression to cirrhosis and hepatocellular carcinoma in patients with CHC, however alcohol intake has been poorly quantified in these studies.
Databáze: OpenAIRE