Surprising lack of association of prior alcohol consumption on hepatitis C infection and hepatic histology
Autor: | Manjushree Gautam, Brenda Horwitz, Swati Patel, Martin Black, Alan W Chang, Frank K. Friedenberg |
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Rok vydání: | 2003 |
Předmět: |
medicine.medical_specialty
Pathology Cirrhosis Hepatology business.industry Gastroenterology Histology Viremia Alcohol Hepatitis C medicine.disease medicine.disease_cause chemistry.chemical_compound Alcohol and health chemistry Hepatocellular carcinoma Internal medicine Medicine business Oxidative stress |
Zdroj: | The American Journal of Gastroenterology. 98:S84 |
ISSN: | 0002-9270 |
DOI: | 10.1016/s0002-9270(03)01014-1 |
Popis: | Background: Chronic alcoholism is common in patients with chronic hepatitis C (CHC) infection. Alcohol can exacerbate liver damage in hepatitis C infection by causing oxidative stress. Heavy alcohol consumption has been associated with higher levels of viremia and more advanced fibrosis. Studies have also suggested that chronic alcoholism causes more rapid progression to cirrhosis and hepatocellular carcinoma in patients with CHC, however alcohol intake has been poorly quantified in these studies. |
Databáze: | OpenAIRE |
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