Laparoscopic versus open radical prostatectomy in high prostate volume cases: impact on oncological and functional results

Autor: Gentile Vincenzo, Innocenzi Michele, Salciccia Stefano, Magnus Von Heland, Cattarino Susanna, Di Quilio Francesca, Gentilucci Alessandro, Fasulo Andrea, Sciarra Alessandro
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Male
Time Factors
medicine.medical_treatment
Biopsy
030232 urology & nephrology
lcsh:RC870-923
Prostate cancer
0302 clinical medicine
Postoperative Complications
Prostate
Medicine
Prospective Studies
Prospective cohort study
Intraoperative Complications
education.field_of_study
Prostatectomy
Organ Size
Middle Aged
prostate cancer
Magnetic Resonance Imaging
Operative
medicine.anatomical_structure
Treatment Outcome
030220 oncology & carcinogenesis
Original Article
Positive Surgical Margin
medicine.medical_specialty
prostate volume
Urology
Population
Operative Time
laparoscopy
Risk Assessment
03 medical and health sciences
Humans
education
Aged
Neoplasm Staging
Surgical Procedures
business.industry
Prostatic Neoplasms
Reproducibility of Results
Perioperative
lcsh:Diseases of the genitourinary system. Urology
medicine.disease
Surgery
Urinary Incontinence
Multivariate Analysis
Linear Models
Prostate surgery
Laparoscopy
Neoplasm Grading
business
Zdroj: International Brazilian Journal of Urology : official journal of the Brazilian Society of Urology
International braz j urol v.42 n.2 2016
International Braz J Urol
Sociedade Brasileira de Urologia (SBU)
instacron:SBU
International braz j urol, Volume: 42, Issue: 2, Pages: 223-233, Published: APR 2016
International Brazilian Journal of Urology, Vol 42, Iss 2, Pp 223-233 (2016)
ISSN: 1677-6119
1677-5538
Popis: Background and objective: To prospectively compare the laparoscopic versus open approach to RP in cases with high prostate volume and to evaluate a possible different impact of prostate volume. Materials and Methods: From March 2007 to March 2013 a total of 120 cases with clinically localized prostate cancer (PC) and a prostate volume>70cc identified for radical prostatectomy (RP), were prospectively analyzed in our institute. Patients were offered as surgical technique either an open retropubic or an intraperitoneal laparoscopic (LP) approach. In our population, 54 cases were submitted to LP and 66 to open RP. We analyzed the association of the surgical technique with perioperative, oncological and postoperative functional parameters. Results: In those high prostate volume cases, the surgical technique (laparoscopic versus open) does not represent a significant independent factor able to influence positive surgical margins rates and characteristics (p=0.4974). No significant differences (p>0.05) in the overall rates of positive margins was found, and also no differences following stratification according to the pathological stage and nerve sparing (NS) procedure. The surgical technique was able to significantly and independently influence the hospital stay, time of operation and blood loss (p0.05). Conclusions: In our prospective non randomized analysis on high prostate volumes, the laparoscopic approach to RP is able to guarantee the same oncological and functional results of an open approach, maintaining the advantages in terms of perioperative outcomes.
Databáze: OpenAIRE
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