Laparoscopic versus open radical prostatectomy in high prostate volume cases: impact on oncological and functional results
| Autor: | Gentile Vincenzo, Innocenzi Michele, Salciccia Stefano, Magnus Von Heland, Cattarino Susanna, Di Quilio Francesca, Gentilucci Alessandro, Fasulo Andrea, Sciarra Alessandro |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
Time Factors medicine.medical_treatment Biopsy 030232 urology & nephrology lcsh:RC870-923 Prostate cancer 0302 clinical medicine Postoperative Complications Prostate Medicine Prospective Studies Prospective cohort study Intraoperative Complications education.field_of_study Prostatectomy Organ Size Middle Aged prostate cancer Magnetic Resonance Imaging Operative medicine.anatomical_structure Treatment Outcome 030220 oncology & carcinogenesis Original Article Positive Surgical Margin medicine.medical_specialty prostate volume Urology Population Operative Time laparoscopy Risk Assessment 03 medical and health sciences Humans education Aged Neoplasm Staging Surgical Procedures business.industry Prostatic Neoplasms Reproducibility of Results Perioperative lcsh:Diseases of the genitourinary system. Urology medicine.disease Surgery Urinary Incontinence Multivariate Analysis Linear Models Prostate surgery Laparoscopy Neoplasm Grading business |
| Zdroj: | International Brazilian Journal of Urology : official journal of the Brazilian Society of Urology International braz j urol v.42 n.2 2016 International Braz J Urol Sociedade Brasileira de Urologia (SBU) instacron:SBU International braz j urol, Volume: 42, Issue: 2, Pages: 223-233, Published: APR 2016 International Brazilian Journal of Urology, Vol 42, Iss 2, Pp 223-233 (2016) |
| ISSN: | 1677-6119 1677-5538 |
| Popis: | Background and objective: To prospectively compare the laparoscopic versus open approach to RP in cases with high prostate volume and to evaluate a possible different impact of prostate volume. Materials and Methods: From March 2007 to March 2013 a total of 120 cases with clinically localized prostate cancer (PC) and a prostate volume>70cc identified for radical prostatectomy (RP), were prospectively analyzed in our institute. Patients were offered as surgical technique either an open retropubic or an intraperitoneal laparoscopic (LP) approach. In our population, 54 cases were submitted to LP and 66 to open RP. We analyzed the association of the surgical technique with perioperative, oncological and postoperative functional parameters. Results: In those high prostate volume cases, the surgical technique (laparoscopic versus open) does not represent a significant independent factor able to influence positive surgical margins rates and characteristics (p=0.4974). No significant differences (p>0.05) in the overall rates of positive margins was found, and also no differences following stratification according to the pathological stage and nerve sparing (NS) procedure. The surgical technique was able to significantly and independently influence the hospital stay, time of operation and blood loss (p0.05). Conclusions: In our prospective non randomized analysis on high prostate volumes, the laparoscopic approach to RP is able to guarantee the same oncological and functional results of an open approach, maintaining the advantages in terms of perioperative outcomes. |
| Databáze: | OpenAIRE |
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