Reduction of portal hypertension by ganglionic blockade

Autor: Richard P. Huemer, John J. Cincotti
Rok vydání: 1971
Předmět:
Zdroj: The American Journal of Digestive Diseases. 16:517-521
ISSN: 1573-2568
0002-9211
DOI: 10.1007/bf02235542
Popis: The effect of the ganglionic blocking agent, trimethaphan camsylate, on the portal venous and systemic arterial blood pressure was evaluated in 58 cirrhotic patients who had esophageal varices secondary to portal hypertension. Portal venous pressure was monitored by splenic-pulp manometry. Trimethaphan induced a mean decrease of 31.0% in portal pressure and 39.3% in arterial pressure. Both decrements were highly significant (P
Databáze: OpenAIRE