Sex hormone profile in human immunodeficiency virus-infected men and it's correlation with CD4 cell counts

Autor: Afroz Jamal, Mohsin Wali, Anubhuti Chitkara, Rajesh Satyapal Taneja, Jyoti Aggarwal, Pulin Kumar Gupta
Rok vydání: 2018
Předmět:
Zdroj: Indian Journal of Endocrinology and Metabolism
Indian Journal of Endocrinology and Metabolism, Vol 22, Iss 3, Pp 328-334 (2018)
ISSN: 2230-8210
DOI: 10.4103/ijem.ijem_694_17
Popis: Background: In human immunodeficiency virus (HIV)-infected men, hypogonadism is the most common endocrinological disorder, and most cases of hypogonadism are secondary. The aim of this study was to find out the hormonal abnormalities in HIV-infected males and it's correlation with CD4 cell counts. Materials and Methods: One hundred HIV-infected male patients were evaluated in the Department of Medicine, Postgraduate Institute of Medical Education and Research and Dr. Ram Manohar Lohia Hospital, New Delhi, India, over a period of 12 months from September 2014 to August 2015 using history, physical examination, routine baseline investigations, and CD4 counts. Free testosterone, dehydroepiandrosterone sulfate (DHEAS), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and prolactin were measured using an overnight fasting sample. Patients were divided into three groups on the basis of CD4 counts (Group A: CD4 counts ≥350/mm3, Group B: CD4 counts between 200 and 349/mm3, and Group C: CD4 counts
Databáze: OpenAIRE