Sex hormone profile in human immunodeficiency virus-infected men and it's correlation with CD4 cell counts
Autor: | Afroz Jamal, Mohsin Wali, Anubhuti Chitkara, Rajesh Satyapal Taneja, Jyoti Aggarwal, Pulin Kumar Gupta |
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Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
Endocrinology Diabetes and Metabolism 030106 microbiology Physiology Physical examination lcsh:Diseases of the endocrine glands. Clinical endocrinology sex hormones Group A Group B 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology Sex hormone-binding globulin Dehydroepiandrosterone sulfate male hypogonadism Medicine 030212 general & internal medicine lcsh:RC799-869 lcsh:RC648-665 biology medicine.diagnostic_test business.industry Prolactin CD4 counts chemistry human immunodeficiency virus/AIDS biology.protein lcsh:Diseases of the digestive system. Gastroenterology Original Article business Luteinizing hormone Hormone |
Zdroj: | Indian Journal of Endocrinology and Metabolism Indian Journal of Endocrinology and Metabolism, Vol 22, Iss 3, Pp 328-334 (2018) |
ISSN: | 2230-8210 |
DOI: | 10.4103/ijem.ijem_694_17 |
Popis: | Background: In human immunodeficiency virus (HIV)-infected men, hypogonadism is the most common endocrinological disorder, and most cases of hypogonadism are secondary. The aim of this study was to find out the hormonal abnormalities in HIV-infected males and it's correlation with CD4 cell counts. Materials and Methods: One hundred HIV-infected male patients were evaluated in the Department of Medicine, Postgraduate Institute of Medical Education and Research and Dr. Ram Manohar Lohia Hospital, New Delhi, India, over a period of 12 months from September 2014 to August 2015 using history, physical examination, routine baseline investigations, and CD4 counts. Free testosterone, dehydroepiandrosterone sulfate (DHEAS), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and prolactin were measured using an overnight fasting sample. Patients were divided into three groups on the basis of CD4 counts (Group A: CD4 counts ≥350/mm3, Group B: CD4 counts between 200 and 349/mm3, and Group C: CD4 counts |
Databáze: | OpenAIRE |
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