Bartter's syndrome with gouty arthritis
Autor: | Shingo Shibata, Masayoshi Abiru, Takashi Ogawa, Yuichiro Fukazawa, Kenjiro Kikuchi, Tetsuji Miura, Osamu Iimura, Yukiyasu Fujise, Yoshiichi Takigami |
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Rok vydání: | 1992 |
Předmět: |
medicine.medical_specialty
Metabolic alkalosis urologic and male genital diseases Excretion Renin-Angiotensin System chemistry.chemical_compound Internal medicine Internal Medicine medicine Humans Hyperuricemia Uremia business.industry Arthritis Gouty Bartter Syndrome General Medicine Middle Aged medicine.disease Angiotensin II Hypokalemia Uric Acid Free water clearance Bartter's syndrome Endocrinology Kidney Tubules chemistry Uric acid Female medicine.symptom business |
Zdroj: | Internal medicine (Tokyo, Japan). 31(9) |
ISSN: | 0918-2918 |
Popis: | A 45-year-old woman with Bartter's syndrome complicated with gouty arthritis is reported. Bartter's syndrome was diagnosed from hypokalemia, metabolic alkalosis, high plasma renin activity, normal blood pressure and attenuated pressor response to exogenous angiotensin II infusion. Serum uric acid was 11.8 mg/dl, the renal clearance of uric acid was low (3.0 ml/min) and fractional excretion of uric acid (FEUA) was 7.0%, being the lower limit of the normal range. Fractional excretion of phosphate was low (5.3%) and fractional free water clearance per fractional distal sodium delivery was 0.51. The mechanism of hyperuricemia in this case is discussed. |
Databáze: | OpenAIRE |
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