Bartter's syndrome with gouty arthritis

Autor: Shingo Shibata, Masayoshi Abiru, Takashi Ogawa, Yuichiro Fukazawa, Kenjiro Kikuchi, Tetsuji Miura, Osamu Iimura, Yukiyasu Fujise, Yoshiichi Takigami
Rok vydání: 1992
Předmět:
Zdroj: Internal medicine (Tokyo, Japan). 31(9)
ISSN: 0918-2918
Popis: A 45-year-old woman with Bartter's syndrome complicated with gouty arthritis is reported. Bartter's syndrome was diagnosed from hypokalemia, metabolic alkalosis, high plasma renin activity, normal blood pressure and attenuated pressor response to exogenous angiotensin II infusion. Serum uric acid was 11.8 mg/dl, the renal clearance of uric acid was low (3.0 ml/min) and fractional excretion of uric acid (FEUA) was 7.0%, being the lower limit of the normal range. Fractional excretion of phosphate was low (5.3%) and fractional free water clearance per fractional distal sodium delivery was 0.51. The mechanism of hyperuricemia in this case is discussed.
Databáze: OpenAIRE