Estimation and comparision of serum β2-microglobulin in oral squamous cell carcinoma and oral leukoplakia

Autor: Arun Tadas, Bhavana Agrawal, R N Mody
Rok vydání: 2016
Předmět:
Zdroj: Journal of Research in Dentistry; v. 4, n. 1 (2016); 18-22
ISSN: 2317-5907
DOI: 10.19177/jrd.v4e1201618-22
Popis: Aim: To estimate and compare serum β2-microglobulin levels in oral leukoplakia and oral squamous cell carcinoma patients with that of control group. Material and Methods: The study was carried out on 70 subjects divided into three groups (20 oral leukoplakia patients, 30 oral squamous cell carcinoma patients and 20 controls). Serum β2-microglobulin was estimated by an enzyme linked immunosorbent assay (ELISA). Results: A significant increase in serum levels of β2-microglobulin was observed in oral squamous cell carcinoma patients as compared to control group. Conclusions: Results of this study suggest that estimation of serum β2-microglobulin can be useful in as biomarker for diagnosis of oral squamous cell carcinoma.
Databáze: OpenAIRE