Estimation and comparision of serum β2-microglobulin in oral squamous cell carcinoma and oral leukoplakia
Autor: | Arun Tadas, Bhavana Agrawal, R N Mody |
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Rok vydání: | 2016 |
Předmět: |
Oncology
medicine.medical_specialty business.industry Beta-2 microglobulin 030206 dentistry General Medicine Gastroenterology Oral leukoplakia stomatognathic diseases 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine Biomarker (medicine) Basal cell 030212 general & internal medicine business |
Zdroj: | Journal of Research in Dentistry; v. 4, n. 1 (2016); 18-22 |
ISSN: | 2317-5907 |
DOI: | 10.19177/jrd.v4e1201618-22 |
Popis: | Aim: To estimate and compare serum β2-microglobulin levels in oral leukoplakia and oral squamous cell carcinoma patients with that of control group. Material and Methods: The study was carried out on 70 subjects divided into three groups (20 oral leukoplakia patients, 30 oral squamous cell carcinoma patients and 20 controls). Serum β2-microglobulin was estimated by an enzyme linked immunosorbent assay (ELISA). Results: A significant increase in serum levels of β2-microglobulin was observed in oral squamous cell carcinoma patients as compared to control group. Conclusions: Results of this study suggest that estimation of serum β2-microglobulin can be useful in as biomarker for diagnosis of oral squamous cell carcinoma. |
Databáze: | OpenAIRE |
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