Bridging the gap between complexity science and clinical practice by formalizing idiographic theories: a computational model of functional analysis
Autor: | Date C. van der Veen, Julian Burger, Robert A. Schoevers, Harriëtte Riese, Sacha Epskamp, Donald J. Robinaugh, Rick Quax |
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Přispěvatelé: | Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Perceptual and Cognitive Neuroscience (PCN), Clinical Cognitive Neuropsychiatry Research Program (CCNP), FdR overig onderzoek, Computational Science Lab (IVI, FNWI), Psychologische Methodenleer (Psychologie, FMG) |
Rok vydání: | 2019 |
Předmět: |
DISORDER
Complex systems medicine.medical_treatment Psychological intervention lcsh:Medicine Development theory PsyArXiv|Social and Behavioral Sciences|Clinical Psychology 0302 clinical medicine bepress|Social and Behavioral Sciences|Psychology|Clinical Psychology Dynamical systems NETWORK Theory development 05 social sciences NONLINEAR DYNAMICS PsyArXiv|Social and Behavioral Sciences|Quantitative Methods|Computational Modeling Computational modeling General Medicine Cognitive behavioral therapy Mental Health Formalizing theories Network analysis medicine.symptom Ordinary differential equations Cognitive psychology Research Article bepress|Social and Behavioral Sciences|Psychology|Quantitative Psychology 050105 experimental psychology Cognitive reappraisal 03 medical and health sciences medicine bepress|Medicine and Health Sciences|Medical Specialties|Psychiatry Humans 0501 psychology and cognitive sciences Computer Simulation Nomothetic and idiographic Functional analysis business.industry Panic disorder lcsh:R Panic Idiographic approach medicine.disease Social learning Psychotherapy PsyArXiv|Social and Behavioral Sciences PsyArXiv|Psychiatry bepress|Social and Behavioral Sciences PsyArXiv|Social and Behavioral Sciences|Quantitative Methods business 030217 neurology & neurosurgery Process-based psychotherapy |
Zdroj: | BMC Medicine BMC Medicine, 18(1):99. BMC BMC Medicine, 18:99. BioMed Central BMC Medicine, Vol 18, Iss 1, Pp 1-18 (2020) |
ISSN: | 1741-7015 |
Popis: | Background The past decades of research have seen an increase in statistical tools to explore the complex dynamics of mental health from patient data, yet the application of these tools in clinical practice remains uncommon. This is surprising, given that clinical reasoning, e.g., case conceptualizations, largely coincides with the dynamical system approach. We argue that the gap between statistical tools and clinical practice can partly be explained by the fact that current estimation techniques disregard theoretical and practical considerations relevant to psychotherapy. To address this issue, we propose that case conceptualizations should be formalized. We illustrate this approach by introducing a computational model of functional analysis, a framework commonly used by practitioners to formulate case conceptualizations and design patient-tailored treatment. Methods We outline the general approach of formalizing idiographic theories, drawing on the example of a functional analysis for a patient suffering from panic disorder. We specified the system using a series of differential equations and simulated different scenarios; first, we simulated data without intervening in the system to examine the effects of avoidant coping on the development of panic symptomatic. Second, we formalized two interventions commonly used in cognitive behavioral therapy (CBT; exposure and cognitive reappraisal) and subsequently simulated their effects on the system. Results The first simulation showed that the specified system could recover several aspects of the phenomenon (panic disorder), however, also showed some incongruency with the nature of panic attacks (e.g., rapid decreases were not observed). The second simulation study illustrated differential effects of CBT interventions for this patient. All tested interventions could decrease panic levels in the system. Conclusions Formalizing idiographic theories is promising in bridging the gap between complexity science and clinical practice and can help foster more rigorous scientific practices in psychotherapy, through enhancing theory development. More precise case conceptualizations could potentially improve intervention planning and treatment outcomes. We discuss applications in psychotherapy and future directions, amongst others barriers for systematic theory evaluation and extending the framework to incorporate interactions between individual systems, relevant for modeling social learning processes. With this report, we hope to stimulate future efforts in formalizing clinical frameworks. |
Databáze: | OpenAIRE |
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