Bridging the gap between complexity science and clinical practice by formalizing idiographic theories: a computational model of functional analysis

Autor: Date C. van der Veen, Julian Burger, Robert A. Schoevers, Harriëtte Riese, Sacha Epskamp, Donald J. Robinaugh, Rick Quax
Přispěvatelé: Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Perceptual and Cognitive Neuroscience (PCN), Clinical Cognitive Neuropsychiatry Research Program (CCNP), FdR overig onderzoek, Computational Science Lab (IVI, FNWI), Psychologische Methodenleer (Psychologie, FMG)
Rok vydání: 2019
Předmět:
DISORDER
Complex systems
medicine.medical_treatment
Psychological intervention
lcsh:Medicine
Development theory
PsyArXiv|Social and Behavioral Sciences|Clinical Psychology
0302 clinical medicine
bepress|Social and Behavioral Sciences|Psychology|Clinical Psychology
Dynamical systems
NETWORK
Theory development
05 social sciences
NONLINEAR DYNAMICS
PsyArXiv|Social and Behavioral Sciences|Quantitative Methods|Computational Modeling
Computational modeling
General Medicine
Cognitive behavioral therapy
Mental Health
Formalizing theories
Network analysis
medicine.symptom
Ordinary differential equations
Cognitive psychology
Research Article
bepress|Social and Behavioral Sciences|Psychology|Quantitative Psychology
050105 experimental psychology
Cognitive reappraisal
03 medical and health sciences
medicine
bepress|Medicine and Health Sciences|Medical Specialties|Psychiatry
Humans
0501 psychology and cognitive sciences
Computer Simulation
Nomothetic and idiographic
Functional analysis
business.industry
Panic disorder
lcsh:R
Panic
Idiographic approach
medicine.disease
Social learning
Psychotherapy
PsyArXiv|Social and Behavioral Sciences
PsyArXiv|Psychiatry
bepress|Social and Behavioral Sciences
PsyArXiv|Social and Behavioral Sciences|Quantitative Methods
business
030217 neurology & neurosurgery
Process-based psychotherapy
Zdroj: BMC Medicine
BMC Medicine, 18(1):99. BMC
BMC Medicine, 18:99. BioMed Central
BMC Medicine, Vol 18, Iss 1, Pp 1-18 (2020)
ISSN: 1741-7015
Popis: Background The past decades of research have seen an increase in statistical tools to explore the complex dynamics of mental health from patient data, yet the application of these tools in clinical practice remains uncommon. This is surprising, given that clinical reasoning, e.g., case conceptualizations, largely coincides with the dynamical system approach. We argue that the gap between statistical tools and clinical practice can partly be explained by the fact that current estimation techniques disregard theoretical and practical considerations relevant to psychotherapy. To address this issue, we propose that case conceptualizations should be formalized. We illustrate this approach by introducing a computational model of functional analysis, a framework commonly used by practitioners to formulate case conceptualizations and design patient-tailored treatment. Methods We outline the general approach of formalizing idiographic theories, drawing on the example of a functional analysis for a patient suffering from panic disorder. We specified the system using a series of differential equations and simulated different scenarios; first, we simulated data without intervening in the system to examine the effects of avoidant coping on the development of panic symptomatic. Second, we formalized two interventions commonly used in cognitive behavioral therapy (CBT; exposure and cognitive reappraisal) and subsequently simulated their effects on the system. Results The first simulation showed that the specified system could recover several aspects of the phenomenon (panic disorder), however, also showed some incongruency with the nature of panic attacks (e.g., rapid decreases were not observed). The second simulation study illustrated differential effects of CBT interventions for this patient. All tested interventions could decrease panic levels in the system. Conclusions Formalizing idiographic theories is promising in bridging the gap between complexity science and clinical practice and can help foster more rigorous scientific practices in psychotherapy, through enhancing theory development. More precise case conceptualizations could potentially improve intervention planning and treatment outcomes. We discuss applications in psychotherapy and future directions, amongst others barriers for systematic theory evaluation and extending the framework to incorporate interactions between individual systems, relevant for modeling social learning processes. With this report, we hope to stimulate future efforts in formalizing clinical frameworks.
Databáze: OpenAIRE