Mortality Risk in Symptomatic Patients With Nonobstructive Coronary Artery Disease

Autor: Millie Gomez, Jonathan W. Weinsaft, Troy M. LaBounty, Fay Y. Lin, Tracy Q. Callister, Daniel S. Berman, Jin Ho Choi, Augustin J. Delago, Allison Dunning, Sunaina Koduru, James K. Min, Leslee J. Shaw
Rok vydání: 2011
Předmět:
Zdroj: Journal of the American College of Cardiology. 58(5):510-519
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2010.11.078
Popis: Objectives We examined mortality risk in relation to extent and composition of nonobstructive plaques by 64-detector row coronary computed tomographic angiography (CCTA). Background The prognostic significance of nonobstructive coronary artery plaques by CCTA is poorly understood. Methods We prospectively evaluated consecutive adults from 2 centers undergoing 64-detector row CCTA without prior documented coronary artery disease (CAD) and without obstructive (≥50%) CAD by CCTA. Luminal diameter stenosis severity was classified for each segment as none (0%) or mild (1% to 49%), and plaque composition was classified as noncalcified, calcified, or mixed. Results During 3.1 ± 0.5 years, 54 intermediate-term (≥90 days) deaths occurred among 2,583 patients (2.09%), with 4 early ( Conclusions The presence and extent of nonobstructive plaques augment prediction of incident mortality beyond conventional clinical risk assessment.
Databáze: OpenAIRE