Mortality Risk in Symptomatic Patients With Nonobstructive Coronary Artery Disease
Autor: | Millie Gomez, Jonathan W. Weinsaft, Troy M. LaBounty, Fay Y. Lin, Tracy Q. Callister, Daniel S. Berman, Jin Ho Choi, Augustin J. Delago, Allison Dunning, Sunaina Koduru, James K. Min, Leslee J. Shaw |
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Rok vydání: | 2011 |
Předmět: |
medicine.medical_specialty
business.industry Plaque composition medicine.disease Coronary artery disease Computed tomographic angiography Stenosis medicine.anatomical_structure Diabetes mellitus Internal medicine medicine Cardiology Radiology business Prospective cohort study Cardiology and Cardiovascular Medicine Clinical risk factor Artery |
Zdroj: | Journal of the American College of Cardiology. 58(5):510-519 |
ISSN: | 0735-1097 |
DOI: | 10.1016/j.jacc.2010.11.078 |
Popis: | Objectives We examined mortality risk in relation to extent and composition of nonobstructive plaques by 64-detector row coronary computed tomographic angiography (CCTA). Background The prognostic significance of nonobstructive coronary artery plaques by CCTA is poorly understood. Methods We prospectively evaluated consecutive adults from 2 centers undergoing 64-detector row CCTA without prior documented coronary artery disease (CAD) and without obstructive (≥50%) CAD by CCTA. Luminal diameter stenosis severity was classified for each segment as none (0%) or mild (1% to 49%), and plaque composition was classified as noncalcified, calcified, or mixed. Results During 3.1 ± 0.5 years, 54 intermediate-term (≥90 days) deaths occurred among 2,583 patients (2.09%), with 4 early ( Conclusions The presence and extent of nonobstructive plaques augment prediction of incident mortality beyond conventional clinical risk assessment. |
Databáze: | OpenAIRE |
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