Pericardial metastases from BRCA1-associated peritoneal cancer. Case report
Autor: | Dariusz Godlewski, Anna Abramowska |
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Jazyk: | angličtina |
Předmět: |
Gynecology
Long lasting medicine.medical_specialty Peritoneal cancer endocrine system diseases business.industry Cancer medicine.disease Gastroenterology female genital diseases and pregnancy complications Cumulative risk medicine.anatomical_structure Oncology Peritoneum Internal medicine Meeting Abstract medicine Lifetime risk Population Risk business Ovarian cancer Genetics (clinical) |
Zdroj: | Hereditary Cancer in Clinical Practice |
ISSN: | 1897-4287 |
DOI: | 10.1186/1897-4287-13-s1-a17 |
Popis: | Women with BRCA1 gene mutations have about 30 to 40 times higher risk of ovarian cancer compared to the population risk (the lifetime risk of BRCA1-dependent ovarian cancer is about 40 percent). Because of the high risk BRCA1 mutations carriers at the age of about 40 are recommended prophylactic salpingo-oophorectomy (after completion of reproductive plans). After the surgery there is still a risk of peritoneal cancer which histologically resembles ovarian cancer, but it is much lower than the risk of ovarian cancer before salpingo-oophorectomy: the cumulative risk of developing cancer of the peritoneum is about 4 percent during 20 years from the removal of ovaries and fallopian tubes. We are going to present a case of long lasting diagnosis of pericardial metastases from BRCA1-associated peritoneal cancer. |
Databáze: | OpenAIRE |
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