Pericardial metastases from BRCA1-associated peritoneal cancer. Case report

Autor: Dariusz Godlewski, Anna Abramowska
Jazyk: angličtina
Předmět:
Zdroj: Hereditary Cancer in Clinical Practice
ISSN: 1897-4287
DOI: 10.1186/1897-4287-13-s1-a17
Popis: Women with BRCA1 gene mutations have about 30 to 40 times higher risk of ovarian cancer compared to the population risk (the lifetime risk of BRCA1-dependent ovarian cancer is about 40 percent). Because of the high risk BRCA1 mutations carriers at the age of about 40 are recommended prophylactic salpingo-oophorectomy (after completion of reproductive plans). After the surgery there is still a risk of peritoneal cancer which histologically resembles ovarian cancer, but it is much lower than the risk of ovarian cancer before salpingo-oophorectomy: the cumulative risk of developing cancer of the peritoneum is about 4 percent during 20 years from the removal of ovaries and fallopian tubes. We are going to present a case of long lasting diagnosis of pericardial metastases from BRCA1-associated peritoneal cancer.
Databáze: OpenAIRE