Naloxone fails to reverse hemorrhagic hypotension
| Autor: | D. F. Brown, R. E. Burr |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Male
Physiology medicine.medical_treatment Blood Pressure Hemorrhage (+)-Naloxone Sodium Chloride Physiology (medical) medicine Animals Saline Chemotherapy Naloxone Narcotic antagonist business.industry Antagonist Rats Inbred Strains Hemorrhagic hypotension Rats Anesthesia Shock (circulatory) Hypotension medicine.symptom Opiate Cardiology and Cardiovascular Medicine business |
| Zdroj: | American Journal of Physiology-Heart and Circulatory Physiology. 251:H468-H470 |
| ISSN: | 1522-1539 0363-6135 |
| DOI: | 10.1152/ajpheart.1986.251.2.h468 |
| Popis: | The effect of opiate antagonist therapy with naloxone on hemorrhagic shock was examined. An equivalent intravenous bolus of naloxone or normal saline had the same pressor effect in conscious, unrestrained, hypovolemic hypotensive rats. The proposal that opiate antagonists are of therapeutic value in the treatment of hemorrhage is questioned. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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