Application of DTI connectivity in lateralization of mTLE

Autor: Mohammad R. Nazem-Zadeh, Esmaeil Davoodi-Bojd, Fariborz Mahmoudi, Susan M. Bowyer, John E. Moran, Hassan Bagher-Ebadian, Andrew Zillgitt, Kost Elisevich, Hamid Soltanian-Zadeh
Rok vydání: 2016
Předmět:
Zdroj: EMBC
DOI: 10.1109/embc.2016.7591978
Popis: Diffusion tensor imaging (DTI) is a noninvasive imaging method for measuring the diffusion properties of the underlying white matter tracts through which epileptiform activity is propagated. This study investigates the structural abnormalities quantified by DTI in mesial temporal lobe epilepsy (mTLE). Fiber tracts passing through 54 anatomical sites in 12 adult mTLE patients and 12 age- and gender- matched controls were identified using DTI tractography. DTI nodal degree (ND) and laterality index were then calculated. ND laterality, after Bonferroni adjustment, showed significant differences for right versus left mTLE in gyrus rectus, insular cortex, precuneus and superior temporal gyrus (p
Databáze: OpenAIRE